(Paper) AIIMS EXAMINATION PAPER WITH ANSWERS EXPLANATIONS YEAR 2002 (Pg-2)
AIIMS EXAMINATION PAPER WITH ANSWERS EXPLANATIONS YEAR 2002
Page-2
26) A 42 year old man was referred with a 2 week history of fever, weakness, bleeding gums. Peripheral smear showed pancytopenia. The bone marrow examination revealed 26 % blasts, frequently exhibiting Auers rods, and mature myeloid cells. An occasional neutrophil with pelger huet anamoly was also noted
Which of the following cytochemical stains is most likely to be positive:
1. Acid phosphatase
2. Nonspecific esterase
3. Myeloperoxidase
4. Toulidine Blue
Ans
This is typical Myleodysplasttic syndrome: RAEB -T
Features 20-29% blasts in bone marrow, 5-29% blasts in peripheral blood, Auer
rods in myeloblasts or other cells of the neutrophil cell line, Auer rods
present in 70% of cases, Ringed sideroblasts may be numerous, Hypercellular
marrow in 80-90% of cases.
27) Dystrophic calcification is seen in:
1. Rickets
2. Hyperparathyroidism
3. Atheromatous plaque
4. Vitamin A intoxication
Ans 3
28) Accumalation of sphingomylein in phagocytic cells is a feature of
1. Gauchers Disease
2. Niemann Pick Disease
3. Tay Sachs Disease
4. Downs syndrome
Ans 2
29) Aschoff Bodies in Rheumatic heart disease show all the following features
except
1. Anitschkow cells
2. Epitheloid cells
3. Giant cells
4. Fibrinoid necrosis
Ans 3
30 ) All of the following features are seen in asbestosis except:
1. Diffuse pulmonary interstitial fibrosis
2. Fibrous pleural thickening
3. Emphysema
4. Calcific pleural plaques
Ans 3
31) Which of the following statements is true regarding drugs used in parkinsonism
1. Amantidine causes ankle oedema
2. Levodopa is particularly effective in reducing tremor
3. Amantidine is more effective then levodapa
4. Antimuscarinics are effective in drug induced parkinsonism
Ans 1 [ Manicks, Stanley Med College] [ Choice 4 seems to be true but only "CENTRAL ANTIMUSCARINCS" are effective in drug induced parkinsonism. Amantidine also causes livedo reticularis, levodopa reduces hypokinesia and rigidity first and lastly tremor. Amantidine action is faster than levodopa but less effective]
32) Prostaglandlins (PGs) have effects on a variety of tissues. The different prostaglandlins may have different effects. Which of the following is not a correct statement.
1. The human arteriolar smooth muscle is relaxed by PGE 2 and PGI 2, where as
TXA 2 and PGF 2 alpha cause vasoconstriction.
2. PGE 1 and PGI 2 inhibit platelet aggregation, where as TXA2 facilitate
aggregation.
3. PGE 2 has marked oxytosic action while PGF 2 alpha has tocolytic action
4. PGE 2 is a bronchodilator where as PGF 2 alpha is a bronchoconstrictor
Ans 3
33) Which of the following diuretics decrease the renal lithium clearance
1. Acetazolamide
2. Hydrochlorthiazide
3. Furosemide
4. Spirolonolactone
Ans 3
34) The following is true for Mycoplasmas except
1. Multiply by binary fission
2. Are sensitive to Beta lactam group of antibiotics
3. can grow in cell free culture media
4. require sterols for growth
Ans 2
35) Inhibition of 5 lipoxygenase is useful in
1. Cardiac Faliure
2. Bronchial Asthma
3. Hepatic Faliure
4. Arthritis
Ans 2
36) Rapid induction of anaesthesia occurs with which of the following inhalational anaesthetics
1. Isoflurane
2. Halothane
3. Desflurane
4. Sevoflurane
Ans (4) ref Lee [ less solublity in blood meAns more rapid induction, however
quicker emergence after discontinuing depends upon solublity and redistribution
in lipids of body as well.]
37) Which muscle relaxant increases intracranial pressure
1. Mivacurium
2. Atracurium
3. Suxamethonium
4. Vecuronium
Ans 3
38) The µ(Mu) opoid receptor is responsible for the following effects except
1. Miosis
2. Bradycardia
3. Hypothermia
4. Bronchodilation
Ans 4
39) Pulmonary fibrosis is a common complication with
1. 6 mercapto purine
2. Vincristine
3. Bleomycin
4. Adriamycin
Ans 3
40) Whuich of the following gas is used to decrease pulmonary artery pressure in adults
1. Nitrous Oxide
2. Nitrogen Dioxide
3. Nitric Oxide
4. Nitrogen
Ans 3
41) The topical use of which of the following antibiotics is not recomended
1. Lignocaine
2. Bupivacaine
3. Cocaine
4. Dibucaine
Ans 2
42) The use of succinylcoline is NOT contraindicated in
1. Tetanus
2. Closed head injury
3. cerebral stroke
4. hepatic faliure
Ans 4
43) Which of the following is the treatment of choice of for cryptococcal meningitis
1. Fluconazole
2. Itraconazole
3. Flucytosine
4. Amphoterecin B
Ans 4
44) The lymphocytopenia seen a few hours after administration of a large dose of prednisolone to a patient with lymphocytic leukemia is due to :
1. Massive lymphocyte apoptosis
2. Bone marrow depression
3. Activation of cytotoxic cells
4. Stimulation of Natural killer cell activity
Ans 1
45) Prolactin secretion will be inhibited by
1. haloperidol
2. GABA
3. Neurophysin
4. Dopamine
Ans 4
46) The production of cervical mucous is stimulated by
1. Progesterone
2. Estradiol
3. Estriol
4. Pregnenolone
Ans 2
47) A travelling nerve impulse does not depolarize the area behind it, because
1. It is hyperpolarized
2. It is refractory
3. It is not self propogating
4. The condition is always orthodromic
Ans 2 [Ref Ganong]
48) A 10 Deg Centigrade decrease in temperature causes decrease in cerebral metabolic rate by
1. 10%
2. 30 %
3. 50 %
4 70 %
Ans (4)
Ref Lee With each one degree fall in temperature cerebral metaboism is reduced
by 6-7%. Also fall in temp leads to rise in serum potassium & acidosis
49) The laboratort report shows values of gonadotropin and ovarian values of the blood sample taken on day 20 of the menstrual cycle of a young woman . Whether her cycle was ovulatory or not may be validly assesed by the reported serum levels of
1. FSH
2. LH
3. Oestradiol
4. Progesterone
Ans 4
50) Which of the following is NOT a usual feature of right middle cerebral artery territory infarct
1. Aphasia
2. Hemiparesis
3. Facial weakness
4. Dysarthria
Ans (1)[ Usually left hemisphere is dominant--its infart leads to aphasia]?
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